TY - JOUR
T1 - A Comprehensive Review on Monkeypox Viral Disease with Potential Diagnostics and Therapeutic Options
AU - Rabaan, Ali A.
AU - Al-Shwaikh, Seham A.
AU - Alfouzan, Wadha A.
AU - Al-Bahar, Ali M.
AU - Garout, Mohammed
AU - Halwani, Muhammad A.
AU - Albayat, Hawra
AU - Almutairi, Norah B.
AU - Alsaeed, Mohammed
AU - Alestad, Jeehan H.
AU - Al-Mozaini, Maha A.
AU - Ashgar, Tala M.Al
AU - Alotaibi, Sultan
AU - Abuzaid, Abdulmonem A.
AU - Aldawood, Yahya
AU - Alsaleh, Abdulmonem A.
AU - Al-Afghani, Hani M.
AU - Altowaileb, Jaffar A.
AU - Alshukairi, Abeer N.
AU - Arteaga-Livias, Kovy
AU - Singh, Kirnpal Kaur Banga
AU - Imran, Mohd
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/7
Y1 - 2023/7
N2 - The purpose of this review is to give an up-to-date, thorough, and timely overview of monkeypox (Mpox), a severe infectious viral disease. Furthermore, this review provides an up-to-date treatment option for Mpox. The monkeypox virus (MPXV) has remained the most virulent poxvirus for humans since the elimination of smallpox approximately 41 years ago, with distribution mainly in central and west Africa. Mpox in humans is a zoonotically transferred disease that results in symptoms like those of smallpox. It had spread throughout west and central Africa when it was first diagnosed in the Republic of Congo in 1970. Mpox has become a major threat to global health security, necessitating a quick response by virologists, veterinarians, public health professionals, doctors, and researchers to create high-efficiency diagnostic tests, vaccinations, antivirals, and other infection control techniques. The emergence of epidemics outside of Africa emphasizes the disease’s global significance. A better understanding of Mpox’s dynamic epidemiology may be attained by increased surveillance and identification of cases.
AB - The purpose of this review is to give an up-to-date, thorough, and timely overview of monkeypox (Mpox), a severe infectious viral disease. Furthermore, this review provides an up-to-date treatment option for Mpox. The monkeypox virus (MPXV) has remained the most virulent poxvirus for humans since the elimination of smallpox approximately 41 years ago, with distribution mainly in central and west Africa. Mpox in humans is a zoonotically transferred disease that results in symptoms like those of smallpox. It had spread throughout west and central Africa when it was first diagnosed in the Republic of Congo in 1970. Mpox has become a major threat to global health security, necessitating a quick response by virologists, veterinarians, public health professionals, doctors, and researchers to create high-efficiency diagnostic tests, vaccinations, antivirals, and other infection control techniques. The emergence of epidemics outside of Africa emphasizes the disease’s global significance. A better understanding of Mpox’s dynamic epidemiology may be attained by increased surveillance and identification of cases.
KW - Mpox
KW - endemic
KW - infectious diseases
KW - monkeypox
KW - orthopoxviruses
KW - outbreak
KW - poxvirus
KW - treatment
KW - viral diseases
KW - zoonosis
UR - http://www.scopus.com/inward/record.url?scp=85175113260&partnerID=8YFLogxK
U2 - 10.3390/biomedicines11071826
DO - 10.3390/biomedicines11071826
M3 - Review article
AN - SCOPUS:85175113260
SN - 2227-9059
VL - 11
JO - Biomedicines
JF - Biomedicines
IS - 7
M1 - 1826
ER -